منابع مشابه
Toll like Receptor in Infectious Diseases
Many studies reported that genetic variation in interleukin-1 (IL-1) receptors/Toll like receptors (TLRs) are susceptible to infectious diseases. TLRs play an important role in the innate immune response to invading pathogens. TLRs are emerging in conditions such as asthma, rheumatoid arthritis, sepsis syndrome, and systemic lupus erythromatosis, suggesting that targeting of TLRs might be usefu...
متن کاملToll-Like Receptor 3 in Liver Diseases
Toll-like receptor 3 (TLR3) is a member of the TLR family that can recognize double-stranded RNA (dsRNA), playing an important role in antiviral immunity. Recent studies have shown that TLR3 is also expressed on parenchymal and nonparenchymal cells in the liver as well as on several types of immune cells. In this review, we summarize the role of TLR3 in liver injury, inflammation, regeneration,...
متن کاملToll-Like Receptor Signaling in Liver Diseases
1Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA 2Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA 3Department of Molecular Microbiology and Immunology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA 4Malari Program, Seattle Biomedical Research Institute, Seattle, WA 98109, US...
متن کاملTargeting Toll-like receptor signaling as a novel approach to prevent ocular infectious diseases
Toll-like receptors (TLRs) play a key role in the innate immune response to invading pathogens. Thus, their discovery has opened up a wide range of therapeutic possibilities for various infectious and inflammatory diseases. In the last several years, extensive research efforts have provided a considerable wealth of information on the expression and function of TLRs in the eye, with significant ...
متن کامل[Role of toll-like receptor 2 in cardiovascular diseases].
Toll-like receptors are the important pattern recognition receptors of innate immune system, which mediate the immunological defence response against pathogen or endogenous damage associated molecules. Recently, more and more researches indicated that Toll-like receptor 2 played vital roles in the pathophysiology of many cardiovascular diseases, including atherosclerosis, coronary diseases, car...
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ژورنال
عنوان ژورنال: Journal of Ancient Diseases & Preventive Remedies
سال: 2016
ISSN: 2329-8731
DOI: 10.4172/2329-8731.1000e123